CHEM
640: Biological Physical Chemistry (3 credits)
Fall 2011
The course presents the basic principles of physical
chemistry with applications to biological systems. Topics include the laws of
thermodynamics, phase equilibria, chemical equilibria, chemical reaction
kinetics and brief introduction to quantum chemistry and spectroscopy.
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Line number: |
11678 |
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Instructor: |
Krzysztof Kuczera, 5090 Malott, phone:
864-5060 ; email: kkuczera@ku.edu |
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Time & Place: |
9:00–9:50 AM, MWF, 2074 Malott |
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Textbook: |
P. Atkins and J. de Paula, Physical Chemistry |
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for the Life Sciences, 2nd Ed., W.H.
Freeman, 2011. |
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Discussion meetings: |
Wednesdays 2:30–3:20, 1003 Malott |
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Thursdays 3:00–3:50, 1003 Malott |
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Office hours: |
T,W 10:00-11:00 am or by appointment |
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Teaching Assistant: |
Hossein Jooya, 1010 Malott, Phone: 864-3053, email: jooya@ku.edu Office hours:
W 11:00-12:00 or by appointment |
The overall course grade will be determined by
the sum of five components
(weights in parentheses):
(on-line quizzes)«(0.15) + (problem portfolio)«(0.10) + (homework)«(0.25)
+ (average of the two hour exam scores)«(0.25) + (final exam score)«(0.25)
Exam dates:
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Exam #1 |
Monday, October 3, in class |
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Exam #2 |
Monday, November 7, in class |
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FINAL |
Thursday, December 15, 7:30–10:00 am |
Quizzes.
On-line quizzes in Blackboard will be
given approximately weekly, aimed at engaging students in systematic reading of
class material.
Problem
solving. Learning of the complex
concepts of physical chemistry cannot be achieved without the experience and
insight gained by problem solving. Solutions to sample problems are given in
the textbook, will be discussed in class, presented on Web site, assigned as
homework and covered in discussion sections. Familiarity with the problems
covered is ABSOLUTELY NECESSARY for success in the exams.
Homework.
Problem sets will be assigned weekly.
Portfolios. To organize the body of problems we will be tackling,
each student will prepare a problem portfolio in a 2-3 inch binder. The
portfolio should contain full solutions to a) problems solved in class b)
correct solutions to homework problems c) solutions to trial exams.
Solution
format. Each problem solution should start on a new page and include:
a)
the problem text
(may be abbreviated, copied and
pasted, etc.)
b)
summary (e.g. Òproblem deals with heat flow in
chemical reactionsÓ)
c)
solution,
including equations and justification in words (e.g. ÒUsing the ideal gas
equation pV = nRT ÉÓ)
d)
final answer:
quantity with correct value and units (+
significant figures)
e)
comments and
discussion when appropriate (i.e. almost always)
Reading: I recommended reading the relevant
chapters of textbook and on-line lecture notes both before and after the
material is covered in class. In order to better understand the material it is
useful to look at alternative presentations of material, such as
0. P. Atkins and J. de Paula, Physical Chemistry for
the Life Sciences, 2nd Ed.,W.H. Freeman, 2011, ISBN 1-4292-3114-9
(class text).
1. Tinoco, Sauer & Wang, Physical Chemistry,
Principles and Applications in Biological Sciences, 3 Ed.
QH345.T56 2002
2. Eisenberg & Crothers, Physical Chemistry with
Applications to the Life Sciences. QD453.2E37 1979
3. Alberty & Silbey, Physical Chemistry.
QD453.2.A45 2001
Electronic
materials. Electronic materials will
be at class website and on Blackboard. Blackboard:
syllabus, announcements, quizzes, homework assignments, grades. Class website: cross-linked lecture notes, sample
problem solutions, study guide, trial exams.
Location: http://oolung.chem.ku.edu/~kuczera/640/640.html
Syllabus
|
Dates |
Topic |
Chapter |
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08/22–08/24 |
Introduction, Gases |
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08/26–09/09 |
The
First Law & Thermochemistry |
1 |
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09/12–09/23 |
The
Second Law & Entropy |
2 |
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09/26–09/30 |
Free
energy |
2 |
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10/03 |
Exam #1 |
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10/05–10/07 |
Phase
equilibria of pure substances |
3 |
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10/12–10/19 |
Mixtures |
3 |
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10/21–11/04 |
Chemical
Equilibrium, Acid-Base Equilibria |
4 |
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11/07 |
Exam #2 |
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11/09–11/14 |
Chemical
Reaction Kinetics |
6 |
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11/16–11/21 |
Reaction
Mechanisms |
7-8 |
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11/28–12/07 |
Quantum
Mechanics & Spectroscopy |
9 |